These glycosaminoglycan ( gag ) chains are long , linear carbohydrate polymers that are negatively charged under physiological conditions , due to the occurrence of sulphate and uronic acid groups 这些粘多糖( gag )链是长条线状的碳水化合物聚合体,在正常生环境下,由于硫酸根和糖醛酸根的存在而处于负电位。
2.
[ objective ] heparin is linear polysaccharides consisting of repeating disaccharide unit backbones of n - acetyl - d - glucosamine that is linked to d - glucuronic acid . the disaccharide repeat unit can be modified to include n - and o - sulfation ( 6 - o and 3 - o sulfation of the glucosamine and 2 - o sulfation of the uronic acid ) . these specific sulfate patterns are involved in the interaction of heparin with other molecules [目的]肝素是由n -乙酰葡萄糖胺与d -葡萄糖醛酸以1 4糖苷键连接起来的重复二糖单位组成的线性多糖,葡萄糖胺可带有n -硫酸基团,可在c6上形成0 -硫酸酯,带有硫酸基团的独特结构参与了肝素与其他分子的相互作用。